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A Smarter Way to Measure FAO in Cells

Fatty acid oxidation (FAO) plays a critical role in cellular energy metabolism, especially during periods of fasting, exercise or metabolic stress, and is tightly linked to mitochondrial health and function. Understanding and measuring FAO is essential for studying metabolic diseases, obesity, diabetes and cancer.

Existing methods for FAO measurement are either indirect, low throughput, or require specialized equipment. The FAO-Glo™ Fatty Acid Oxidation Assay overcomes these limitations by enabling direct detection of FAO in a high-throughput-compatible, plate-based format requiring only a conventional luminometer.

Key Features

Direct and reliable measurement of FAO in living cells
Simple, plate-based format compatible with HTS
No radioactivity or specialized instrumentation required

Product Page

Bar chart comparing control vs. 20µM etomoxir showing reduced luminescence in HEK293 cells.

Bar chart comparing control vs. 10µM resveratrol showing increased luminescence in HepG2 cells.

The FAO-Glo™ Assay detected both inhibition and stimulation of FAO. HEK293 cells were treated with 20µM etomoxir (inhibitor, above). HepG2 cells were treated with 10µM resveratrol (activator, below).

Streamlined dsRNA Detection for Quality Assurance

Double-stranded RNA (dsRNA) is a critical impurity in in vitro- transcribed mRNA therapeutics and can trigger unwanted immune responses. Reliable dsRNA detection is essential to ensure RNA quality and product safety.

Graphic of TLR3 assay showing dsRNA activation and luminescent signal.

The TLR3 Bioassay enables sensitive, mechanism-based detection of immunostimulatory dsRNA in a convenient thaw-and-use format.

Mechanism-of-action detection via human TLR3 activation
Ready-to-use cells – No cell culture required
Responsive to different dsRNA lengths, sequences, and delivery methods
Luminescent readout for robust, quantitative results
Ideal for QC, process optimization, and immunogenicity risk assessment

Product Details

Accelerate IgG Quantification in Antibody Discovery Workflows

Accurate IgG quantification is essential for therapeutic antibody development, clone screening, and cell line optimization. Whether you're tracking expression levels in CHO cell cultures or comparing transfection efficiency, rapid and reliable data enables smarter decisions.

Lumit® IgG Titer Immunoassays deliver fast, consistent results for human, mouse, and rabbit IgG. The no-wash, mix-and-read format integrates seamlessly into high-throughput workflows, accelerating your development process with minimal hands-on time.

Key Benefits

Fast Results: Obtain measurements in as little as 20 minutes
High Sensitivity: Detect IgG concentrations down to 0.4 ng/mL
Broad Applicability: Quantify all human IgG subclasses and multiple isotypes
Streamlined Workflow: No-wash, add-mix-read protocol suitable for high-throughput workflows

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Over 30 Scientific Brochures – Just a Click Away

Promega offers more than 30 in-depth brochures and guides covering topics such as nucleic acid analysis, cell biology, protein analysis, and drug development. Whether you're interested in automated DNA purification, 3D cell culture, or mass spectrometry, you'll find expertly curated knowledge – all in one place.

All materials are available as free PDF downloads or can be requested as printed copies.

Explore the full collection.

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